The Connection Between GABA and Parkinson’s Disease

To understand Parkinson’s Disease, it is important to understand the brain and its function related to the disease. Parkinson’s Disease is a progressive disease of the Central Nervous System, progressive meaning that symptoms, such as slowness of movement (bradykinesia), stiffness and tremors, and more will progress and worsen overtime. When dopamine producing neurons in a…

The Role of TWEAK/Fn14 Signalling in the MPTP-Model of Parkinson’s Disease

In 1985, the discovery of a neurotoxin called 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) changed the lives of six Californians. The young people were recreation drug users, who happened to purchase a synthetic form of heroin that, unfortunately, caused them all to simultaneously develop Parkinson’s disease (Palfreman, 2014). Parkinson’s is a progressive disorder that attacks the nervous system (specifically…